This is why Gaspari Nutrition chose highly branched cluster dextrin for what we consider to be the gold standard of recovery and performance drinks. This high molecular weight carbohydrate has a special helical structure, which gives it unique properties unlike many of the corn starches or polysaccharides out there. I'll be real with you and say this stuff isn’t cheap, but you certainly pay for what you get, and highly branched cluster dextrin is unlike any carb source I've found – especially if you want to control blood sugar levels and gut issues.
Wow! Amazing article. I don’t read blogs regularly, but I’ll be reading more of yours. I am on day 11 of a fast to get me into ketosis; 7 days bone broth and now on day-4 water only. Intentions are weight loss (10# down, 15# more to go) and immunity improvement/gut help. Planning 9 days of whey water, fermented veggies and mad probiotics when the water days are done (day 14?). After this fast I want to stay fat adapted, start training again and get down to 8% body fat. I believe you have cut that journey significantly with this article. Thank you.
When glucose levels are low, especially over time, most cells will switch to using ketone bodies for fuel. Ketones allow cells to be metabolically flexible, so to speak. Even the brain and nerve cells, which are heavily dependent on glucose can utilize ketone bodies for fuel. This ability of most normal cells to use ketones when glucose is unavailable indicates that their cellular mitochondria are healthy and functioning properly.
Josh Axe, a doctor of natural medicine and clinical nutritionist, estimates that about 25% of people who try a ketogenic diet experience these symptoms, with fatigue being the most common. “That happens because your body runs out of sugar to burn for energy, and it has to start using fat,” he says. “That transition alone is enough to make your body feel tired for a few days.”
Julie Hand is a certified holistic health and nutrition counselor (Institute for Integrative Nutrition), personal fitness trainer (National Personal Training Institute), and yoga teacher (Kripalu Center for Yoga & Health). Though she can’t resist trying every science-backed health tip, she also has a penchant for crystals and astrology (don’t judge). You can find her walking the beach (coffee in hand, of course) and practicing the ukulele on weekends.
I don’t understand all the negative reviews at all. I didn’t buy this product to throw me into ketosis. I bought it as an energy supplement, I could take that is keto friendly. I love this product, am actually ordering my second bottle. It is a clean energy boost, no jitters, crashing or anxious feelings. I am already keto adapted it, didn’t throw me out of ketosis, nor did it put me in it. I just wanted a nice boost, which it works perfectly!
I like this product a lot. I am on my 2nd bottle now and I'm working on low carb/ketogenic lifestyle. this has helped with keeping me out of energy crash and burns, no jitters, and no headaches. If you are a coffee drinker it specifically says to avoid more caffeine if you take the full dose (3 capsules) during the day, just so you know. (Guarana is a source of caffeine). Everyone is different. I started with 1 capsule then worked my way up to 3 within a few days to see how my body handled it.
Maintain adequate protein intake. Too little protein and you lose muscle mass and starve the few parts of your body that can’t use ketones as an energy source, like portions of your red blood cells, kidneys and brain. Too much protein and you inhibit ketone production. Make sure you consume enough protein to support your vital functions, but not too much that protein becomes your alternate glycogen source.
In other words, I personally found that while following “strict ketosis”, things became eerily similar to the days in college when I was a competitive bodybuilder pursuing sub-3% body fat percentages. I simply wasn’t the most fun guy to hang out with in social situations due to my extreme dietary restrictions, the intense self-control became nearly exhausting, and when I traveled, I missed out on many culinary experiences, such as homemade ravioli in Rome, freshly baked crostinis in the Basque regions of Spain, and Korean rice bowls in Seoul.
Fortunately, Drs. Kevin Hall and Juen Guo had the same burning question. In 2017, they analyzed the data and published a meta-analysis of controlled feeding studies that compared diets of equal calorie and protein content with variations in carbohydrate and fat content.  By filtering out the diet data in this way, the researchers could finally find out whether restricting carbs or limiting calories is more important when it comes to weight loss.
Acetone is a molecule that results from the breakdown of acetoacetate. Acetone is commonly referred to as a ‘waste product’ as it is less readily used as energy compared to BHB (although some studies have shown that acetone can be oxidised as a fuel4. That said, some evidence suggests that it is responsible for the antiseizure effects of ketogenic diets so in may not be completely inert. At low levels acetone in the breath corresponds well to levels of ketones in the blood 12,13, however this is not the case as blood BHB levels increase 13 and if the increase is rapid, such as with exogenous ketone consumption11.
Thorne Research has decided to discontinue their Glycofuse product, right when I started using it! Current inventory is expected to run out in June or July. I contacted them to ask if it was being replaced with a new product and at this time they are not able to answer that question, and suggested checking back in with them in June/July. Short of stocking up on a case of it, do you have another recommended product that is as clean & functional as the Glycofuse? This recipe in the blog post above has been working great for me this last month. I’m bummed I’m already going to have to switch it up again!
Your glycogen stores can still be refilled while on a ketogenic diet. A keto diet is an excellent way to build muscle, but protein intake is crucial here. It’s suggested that if you are looking to gain mass, you should be taking in about 1.0 – 1.2g protein per lean pound of body mass. Putting muscle on may be slower on a ketogenic diet, but that’s because your total body fat is not increasing as much.5Note that in the beginning of a ketogenic diet, both endurance athletes and obese individuals see a physical performance for the first week of transition.
"Listening to podcasts while I run has completely changed my fitness routine. I thought I hated running, but what I hated was pop music. Keeping my mind engaged has helped me push passed physical barriers. Podcasts about keto, fitness, and nutrition is motivating to me to learn about my body while I’m actively working it. My favorite podcasts are Keto for Normies, The Keto Savage podcast, Seth Godin's podcast and Hiding in the Bathroom."
This is because you get rid of the foods that cause high blood sugar, also known as glucose. Glucose is the easiest way for your body to get energy, but it can lead to energy crashes if you get too much in a short time. To get rid of the glucose and use it up, the body needs to produce insulin. As we produce more and more, our bodies become resistant to it, and this can lead to diabetes.
That can be a shock to the body. “One of the challenges that many people encounter when they try the ketogenic diet for the first time is the drastic lack of energy that is experienced in the first few days. This is the time when the body is learning to use fat for energy rather than readily available carbs,” says Susan Kieffer, DBA, the department chair for the School of Nursing at Purdue University Global. “You can feel very tired during this time and even a little fuzzy in your thinking.”
Wondering what fits into a keto diet — and what doesn’t? “It’s so important to know what foods you’ll be eating before you start, and how to incorporate more fats into your diet,” says Kristen Mancinelli, RD, author of The Ketogenic Diet: A Scientifically Proven Approach to Fast, Healthy Weight Loss, who is based in New York City. We asked her for some guidelines.
Amazing article – gonna have to print it and read it again. To much to break down in one sitting. Thanks Ben – you’ve pulled together so much insight and references that’s given me greater confidence and conviction. I’m 50 and use to be super active and a seasoned athlete but after a few ‘mid life surgical interventions’ I had to find a better way… Ketogenics has been that for me… no more inflammation… I can’t tell you how great it’s been to be pain free! Keep leading from the front.
In its 2016 report “Healthy Eating Guidelines & Weight Loss Advice,” the Public Health Collaboration, a U.K. nonprofit, evaluated evidence on low-carbohydrate, high-fat diets. (The Keto diet falls under the LCHF umbrella.) Among 53 randomized clinical trials comparing LCHF diets to calorie-counting, low-fat diets, a majority of studies showed greater weight loss for the Keto-type diets, along with more beneficial health outcomes. The collaboration recommends weight-loss guidelines that include a low-carbohydrate, high-fat diet of real (rather than processed) foods as an acceptable, effective and safe approach.
One of the diets that implement these principles is the low-carb ketogenic diet. It primarily consists of highly-satiating foods like meat and low-carb vegetables while cutting out all carb-ridden, highly-palatable foods. By eating in this way, most people experience tremendous amounts of fat loss — not because it lowers insulin levels, but because keto dieters tend to eat significantly fewer calories than high-carb dieters without realizing it.
“If you have too many carbohydrates, you’re going to build up your glycogen stores, and it’s going to be very hard for you to get back into ketosis,” she says. She says to think about your glycogen stores, which are your body’s supply of stored carbohydrates, as a gas tank. “As long as we don’t let that tank dip over, we can deplete it pretty quickly again and get back into ketosis,” she says. “But as soon as we go beyond that three or four days [off keto], our tanks flood over and you start to actually store some of that glucose as fat, and it becomes very difficult to deplete that tank again and get back into ketosis.”
Due to the high-quality design and data of the study, it was published in the Journal of American Medicine, one of the most prestigious research journals in the world. The research team stated that “in this study of overweight and obese premenopausal women, those assigned to follow the Atkins diet had more weight loss and more favorable outcomes for metabolic effects at 1 year than women assigned to the Zone, Ornish, or LEARN diets.” 
Eating out while going keto can be tricky. Planning ahead helps you know where your next snacks and meals will come from, so you aren’t tempted to reach for an easy—high-carb—fix, like fast food. Each week, plan out everything from meals to snacks and if you’re using an app, go ahead and fill in your estimated macronutrients ahead of time. This will help you get an idea of your overall intake, so you can make adjustments to reach your daily goals more easily. Get started by planning to make these 10 keto recipes so good you’ll never know you’re on a diet.
Recently, many people have begun to question the usefulness of BMI as a general indicator. A sizable amount of people who may be overweight or even obese may be classified as such even though they have a high amount of muscle. Conversely, people with a “healthy” or low BMI may have a high level of body fat and actually be at a greater risk for developing health problems. [5, 6]
Wow! Such an informative article! A lot to take in! Loving that you mentioned the KETO//OS! I’ve actually lost 10 lbs in 3 weeks! Kinda cool. I haven’t heard of the other products but I’m excited the check them out! Also, the breath tool is new to me. Thank you! If anyone wants to checkout my testimonial with epilepsy, weight loss on the KETO//OS you can read it here: http://bit.ly/keto-os
At the beginning of the year I was counting calories, I was losing weight but I was eating the same thing....every day....never deviating. I lasted 4 months. The lowest I ever hit was 325, starting from 347. I mean that is not bad, and I was losing weight, but I was so bored with my food. Since starting Keto, I am already down to 328 IN TWO WEEKS. I am shocked. I had to have my wife hide the scale, because I kept standing on it not believing what I was seeing. I am eating so well right now.
Thanks for all of the great info!! I have Hashimoto’s and would really like to try a high fat/low carb diet. You mentioned that this might not be a good option for people with thyroid issues. How do you recommend I modify my diet to lose weight taking into consideration the Hashimoto’s. I take Westhroid, a non-synthetic thyroid supplement to help with my sluggish thyroid. Thanks so much for any advice you can give me. :)
You should be lowering your carb intake sufficiently, especially if your diet is regularly high in carbs. When you eat carbs, they’re broken down into glucose, which spikes blood sugar levels. This causes strong insulin levels to combat the spikes, resulting in fat storage and insulin resistance. With the keto diet, you should be getting about 10% of your energy from carbs, 15-25% from protein, and 70% or more from fat.
I started low carb to help reduce inflammation in my body. And have better mental clarity. Weight loss is an added benefit. I’ve only lost 25lb. since January, not a lot but ill take it. I found it too hard to track the amount of protein, carb, fats. I try to stay at 20g carb ,6 oz. Protein and fill in with buttered veg. Coconut oil MCT oil olive oil. So far I’m doing ok I think. Everyone needs to find what works for them.
This doesn’t mean that you can never have some of your favorite foods again. Once you get past the adaptation phase and you have tested that you are in Ketosis, you can start experimenting with Keto versions of the foods you don't want to give up. Here are a few simple Keto recipes to start with. If you're looking for ready-to-eat Keto-friendly options, check out Country Archer Meat Sticks, Cuvee Coffee and FBOMB nut butters.
Wilder's colleague, paediatrician Mynie Peterman, later formulated the classic diet, with a ratio of one gram of protein per kilogram of body weight in children, 10–15 g of carbohydrate per day, and the remainder of calories from fat. Peterman's work in the 1920s established the techniques for induction and maintenance of the diet. Peterman documented positive effects (improved alertness, behaviour and sleep) and adverse effects (nausea and vomiting due to excess ketosis). The diet proved to be successful in children: Peterman reported in 1925 that 95% of 37 young patients had improved seizure control on the diet and 60% became seizure-free. By 1930, the diet had also been studied in 100 teenagers and adults. Clifford Barborka reported that 56% of those older patients improved on the diet and 12% became seizure-free. Although the adult results are similar to modern studies of children, they did not compare as well to contemporary studies. Barborka concluded that adults were least likely to benefit from the diet, and the use of the ketogenic diet in adults was not studied again until 1999.
The metabolic theory states that the root cause of cancer is a defect in mitochondrial energy production or ‘an irreversible injuring in respiration’91. Once the cells ability to produce energy is compromised, this is hypothesised to lead to the subsequent accumulation of changes that make the cell cancerous92. A key change is decreased mitochondrial glucose metabolism in cancer cells. Cancer cells ferment glucose to lactate (which happens outside of the mitochondria) at a much higher rate than normal cells93, in a change called ‘The Warburg Effect.’ This implicates damage to the mitochondria and failure in energy production as a central process of cancer progression.