And what I’m writing has nothing to do with taking supplements to induce ketosis or whatever. I believe these things are covered in Volek & Phoney’s book The Art and Science of Low Carb Living, which I would have thought you to be very familiar with. The iodine stuff you can read about in Iodine, Why We Need, Why We Can’t Live Without It by Brownstein.
I’ll warn you: when you first start using BHB salts like KetoCaNa, it can cause some temporary GI upset until you get acclimated to use. For me, this manifested in just a little bit of gas and bloating that subsided after about one week of use. Additionally, you should know that this product contains salt, so it counts as part of your daily salt intake.
Keto meals seemed so heavy and rich to me, and it just wasn't how I was used to eating. Plus, I consider myself a flexitarian, so the thought of eating more meat—and more often than I typically would—gave me pause. Dr. Axe assured me that even vegetarians could pull off a keto diet if they planned well enough. (Vegans can, too.) That said, he's a proponent of animal products and red meat specifically, because of the iron it provides for women (who are more susceptible to deficiency) and because it can bolster energy when carbs are lacking. (These Are the Other Things Vegetarians Need to Be Aware of Before Going Keto.)
I’ve not been extremely diligent on tracking my calories, carbohydrates and macros. I’m a pretty accurate ball park guesser though.😬 I resist eating anything that is not keto friendly. I count carbs in my mind and try to stay below 20 grams a day. I carefully ballpark my calories per day keeping around 1400 to 1700. I walk 4 to 5 miles every single day,no matter what. I only drink water and black coffee, nothing else. I NEVER snack. I eat twice per day starting at high noon and eat my dinner/final meal sometime between 6:00 or 8:00pm. Which makes my intermittent fasting 16/18 - 6/8. I’ve tested my blood for ketosis a few times and about half of the time I’m in ketosis... but rarely does a week go by that I don’t lose some weight, so I’ve quit testing for ketosis.
Wrong! Dietary cholesterol has been shown to not increase blood cholesterol – check this article here. And fat is healthy when consumed as part of a nutritious meal. As pointed out in this study, a Low Carbohydrate Diet resulted in decreased bodyweight, abdominal circumference, diastolic blood pressure, triglycerides, insulin, and an increase in high-density lipoprotein cholesterol (the good stuff).
Implementing the diet can present difficulties for caregivers and the patient due to the time commitment involved in measuring and planning meals. Since any unplanned eating can potentially break the nutritional balance required, some people find the discipline needed to maintain the diet challenging and unpleasant. Some people terminate the diet or switch to a less demanding diet, like the modified Atkins diet (MAD) or the low-glycaemic index treatment (LGIT) diet, because they find the difficulties too great.[41]
So, the other day I bought some broccoli and I was staring at the stems thinking "I know I can do something besides just slice and sauté these (I am aware that people rice them, but now that bagged frozen riced cauliflower is a thing I will never rice anything again) I pulled out my mandolin and sliced them up figuring i could ten sauté or do something else, and then realized that they were the perfect "Chip" size! First I ate some raw with labne (yogurt cheese) Delicious! Very good option for when you want to dip something! Then today decided to try frying them...
It is known that different dietary components exert some effects on gut microbiome composition, mainly in relation to obesity and inflammatory states. In general, a Mediterranean diet has a positive effect while a high-protein diet seems to have detrimental effects due to putrefaction phenomena (Lopez-Legarrea et al., 2014; Flint et al., 2015). Few data are available at this time about the effects of KD on gut microbiota. For example, a study by Crawford et al. (2009) investigated the regulation of myocardial ketone body metabolism by the gut microbiota and demonstrated that, during fasting, the presence of gut microbiota improved the supply of ketone bodies to the heart where KBs were oxidized. In the absence of a microbiota, low levels of KB was associated with a related increase in glucose utilization, but heart weight was still significantly reduced. The myocardial-mass reduction was completely reversed in germ-free mice feeded with a ketogenic diet. Regarding food control we can hypothesize that the particular metabolic state of ketosis could provide some benefit to weight and food control via synergic actions between butyrate production by gut bacteria and circulating high blood ketones (Sanz et al., 2015).

Wilder's colleague, paediatrician Mynie Peterman, later formulated the classic diet, with a ratio of one gram of protein per kilogram of body weight in children, 10–15 g of carbohydrate per day, and the remainder of calories from fat. Peterman's work in the 1920s established the techniques for induction and maintenance of the diet. Peterman documented positive effects (improved alertness, behaviour and sleep) and adverse effects (nausea and vomiting due to excess ketosis). The diet proved to be successful in children: Peterman reported in 1925 that 95% of 37 young patients had improved seizure control on the diet and 60% became seizure-free. By 1930, the diet had also been studied in 100 teenagers and adults. Clifford Barborka reported that 56% of those older patients improved on the diet and 12% became seizure-free. Although the adult results are similar to modern studies of children, they did not compare as well to contemporary studies. Barborka concluded that adults were least likely to benefit from the diet, and the use of the ketogenic diet in adults was not studied again until 1999.[10][14]


Others consider the keto diet a short-term solution for weight loss. Tyler Drew, a 34-year-old real estate broker from Los Angeles, first read about the diet on Reddit and used it to lose 45 pounds in six months before returning to a traditional diet. While on the keto diet, Drew’s cholesterol levels improved, even though a typical day of eating involved bacon at both breakfast and dinner.

It can also be a challenge not to overindulge on those days off the diet. “For somebody who’s been a carb addict or a sugar addict before going on the diet, all of those cravings for those sugars and those carbs come back pretty strong,” Devine says. “It’s kind of like saying, ‘I’m going to stop smoking, but I’m going to have one cigarette a month.’ Good luck.”

I follow keto and got off 2-Insulins that equaled 5 shots per day and metformin pills @ 1000 mg twice a day and 1 kidney med. Keto has changed my life fior the better. I’m also a health coach for weight loss and nutrition and everyone is different when it comes to weight loss and health. My final #s -95 lbs/22 pants to size 8 and 2x too to small and feel and look great inside and out.


Eat the right amount of protein. Too much protein can increase insulin levels and decrease ketone levels, while not consuming enough protein can cause you to burn muscle rather than fat. If you exercise, protein levels should be hovering around 0.8g – 1.0g protein per lean pound of body mass a day. This helps with muscle mass retention and growth. However, if you are not exercising – your protein intake doesn’t need to be as high. A protein intake of 0.6g – 0.8g of protein per lean pound of body mass is going to be fine for sedentary individuals.
I had the same experience as you with Keto. I lost over 40 lbs. but did not have any energy and I did not have the carefree enjoyment of my life with family, friends, or myself. Was not for me either. I still eat healthy as I am a critical care nurse and I workout 5-6 days a week. There is much less stress without Keto in my life and most definitely much more healthy foods and higher spirits! 🙂
Ketone esters (BHB-BD) could help to accelerate glycogen resynthesis32. After exercise that depletes muscle glycogen, the muscle uses carbohydrate from the diet to replenish these stores. An experiment was carried out where athletes undertook depletive exercise and then were given a ketone drink (or carbohydrate placebo) as well as glucose intravenously to maintain a high blood level (10mM). In this experiment, when the recovery drink contained ketone ester, more glucose was infused in order to maintain blood glucose at 10 mM, and muscle glycogen levels were 50% higher. However, the evidence is not conclusive: another study. 31 found that adding ketone ester to a protein and carbohydrate recovery drink did not enhance the normal rate of glycogen re-synthesis.  
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The BBB, largely formed by the brain capillary endothelial cells, provides a protective barrier between the systemic blood and the extracellular environment of the CNS. Passage of FAs from the blood to the brain may occur either by diffusion or by proteins that facilitate their transport. Studies indicate that FATP-1 and FATP-4 are the predominant FA transport proteins expressed in the BBB based on human and mouse expression studies (Mitchell et al., 2011).
In some cases epilepsy cannot be treated successfully using anticonvulsant medications. In some cases where drugs have failed, the ketogenic diet has been widely documented to deliver transformative seizure control, reducing frequency by anywhere between 40-90%43. Whilst the exact mechanisms underlying the beneficial effect of the ketogenic diet are unclear, the hypothesised mechanisms include:
In 2017, Drs. Kevin Hall and Juen Guo published a meta-analysis of controlled feeding studies that compared diets of equal calorie and protein content with variations in carbohydrate and fat content. By designing the study in this way, the researchers could finally find out whether restricting carbs or limiting calories is more important when it comes to weight loss.
Then there’s medium chain triglycerides (MCT’s). Most dietary fat has to be converted into water soluble molecules that then need to enter the liver via your lymph system. Your liver then converts these molecules to fatty acids and ketone bodies. But unlike most other forms of dietary fats, MCT’s can enter your liver directly without having to go through your lymph system. This means that consuming MCT’s gives your body an opportunity to quickly produce ketone bodies.
I’m brand new to the Keto scene. Just started the diet on tuesday. There are so many supplements listed here. Is there a place to start? Like only starting with a couple? What about blood testing, do you recommend it it and how often and should i even be testing in the first month. Any help is greatly appreciated. You have the most informative articles I’ve been able to find.
The bulk of research suggests that the ketogenic diet is more effective than conventional diets in helping you lose weight and shed body fat. One of the reasons why the ketogenic diet provides such reliable weight loss results is because it consists primarily of highly-satiating whole foods like meat, high-fat dairy, and low-carb vegetables while removing all carb-rich, sugar-laden processed foods from the diet. By eating in this way, you will feel full while eating fewer calories and losing weight.
So if your high-fat diet includes a high amount of roasted seeds or roasted nuts, nut butters, heated oils such as heated coconut oil or heated extra virgin olive oil, barbecued meats or meats cooked at very high temperatures, then your triglyceride count is going to go up. You should have triglycerides that are less than 150mg/dL, and a triglyceride to HDL ratio that is no more than 4:1, and in most of the healthiest people I’ve worked with, triglycerides are under 100 and the triglyceride to HDL ratio is less than 2:1. If your ratio is whacked, your ketotic diet isn’t doing you any favors.

Probably, and there are a few reasons why, Keatley says. For starters, people usually reduce their daily caloric intake to about 1,500 calories a day because healthy fats and lean proteins make you feel fuller sooner—and for a longer period of time. And then there’s the fact that it takes more energy to process and burn fat and protein than carbs, so you're burning slightly more calories than you did before. Over time, this can lead to weight loss.


Amazing article – gonna have to print it and read it again. To much to break down in one sitting. Thanks Ben – you’ve pulled together so much insight and references that’s given me greater confidence and conviction. I’m 50 and use to be super active and a seasoned athlete but after a few ‘mid life surgical interventions’ I had to find a better way… Ketogenics has been that for me… no more inflammation… I can’t tell you how great it’s been to be pain free! Keep leading from the front.

“The argument is that after decades of abusing your body with carbohydrates and thus creating insulin resistance, your body is not going to magically heal itself from a measly 30 days on a low-carb eating plan,” she explains. “If you need things to celebrate while you wait for the scale to start ticking down, look toward your other accomplishments—body composition, pictures, and measurements after three months.”
"I enjoy what I do on a daily basis with Instagram and the interactions I have within the keto community. The relationships extend beyond keto. I started an Instagram account to keep himself accountable and have since made countless friendships with people all over the world. I receive frequent messages from people saying thank you and it motivates me to stay involved."

For patients who benefit, half achieve a seizure reduction within five days (if the diet starts with an initial fast of one to two days), three-quarters achieve a reduction within two weeks, and 90% achieve a reduction within 23 days. If the diet does not begin with a fast, the time for half of the patients to achieve an improvement is longer (two weeks) but the long-term seizure reduction rates are unaffected.[43] Parents are encouraged to persist with the diet for at least three months before any final consideration is made regarding efficacy.[9]

Acetoacetate diester did not improve performance37: a different ketone ester to that used by Cox et al (an acetoacetate diester) decreased cycling performance by 2% given before a 50’ cycling race. Reasons for the difference in findings could be: this ketone ester drink was given along with a can of diet cola 30 mins before exercise and caused GI upset in many athletes. Delivering acetoacetate causes the muscle cells to become more ‘oxidised,’ which is a less favourable state for ATP production. Risk of some gastrointestinal upset with all ketone supplements. The dose, tonicity, time taken before competition and overall volume of a ketone drink will affect how easy it is to tolerate. Many athletes take ketone supplements without side effects, however there are differences between individuals, so practice with ketone supplements in training is advisable to ensure they don’t experience any GI side effects in competition. Geoff Woo discussed this study in a blog post.
Depending on how you choose your fats, the keto diet can contain an abundance of saturated fat, which raises levels of dangerous LDL cholesterol and causes atherosclerosis, the buildup of fats and cholesterol in the arteries. If you decide to go keto, have a doctor monitor your cholesterol levels monthly to ensure you remain within a healthy range.
Furthermore, the participants who ate the low-carbohydrate diet lost an average of 0.8% body fat while those that ate the low-fat diet gained an average of 0.7% body fat. [18] This suggests that a higher fat diet may improve may lead to more favorable changes in body composition. Subjects in both groups notably reduced their waist circumference. [18] However, the reduction was greater for the low-carbohydrate group. [18]
Let’s hold up a sec. Allow me to introduce you to the DIETFITS Randomized Clinical Trial, published in February 2018 in the Journal of the American Medical Association. DIETFITS, which stands for Dietary Intervention Examining the Factors Interacting with Treatment Success, succeeded in busting a slew of dietary theories. Microbiome is responsible for everything? Nope. Predisposition to success on one diet based on genetics? Nah. Low carb over low fat? Uh-uh.
At the beginning of the year I was counting calories, I was losing weight but I was eating the same thing....every day....never deviating. I lasted 4 months. The lowest I ever hit was 325, starting from 347. I mean that is not bad, and I was losing weight, but I was so bored with my food. Since starting Keto, I am already down to 328 IN TWO WEEKS. I am shocked. I had to have my wife hide the scale, because I kept standing on it not believing what I was seeing. I am eating so well right now.
In this study by Dr. Dominic D’Agostino it is also mentioned that your blood brain barrier (BBB) “is relatively impermeable to most hydrophilic substances, such as ketone bodies. Therefore, the transport of ketones across the BBB is highly dependent on specific carrier-mediated facilitated transport by a family of proton-linked monocarboxylic acid transporters”. Basically, what this means is that MCT powder may act as a carrier to shuttle the ketone bodies across the BBB.
One hypothesised contributor to neuronal death is insufficient energy production, secondary to impaired mitochondrial function. However, it is unclear if this is in fact a cause or effect of PD. Whatever the case may be, patients with PD have been shown to have impaired mitochondrial energy production in the brain59 and lower brain glucose utilisation60. Another factor may be neuro-inflammation, which is also common in PD, and is thought to lead to further accumulation of Lewy Bodies and neuronal death.
An increase in fat burning ability could improve endurance capacity: as body fat represents a larger store of energy (150,000 kCal) compared to carbohydrate (2000 kCal), a greater ability to burn fat during exercise could prolong endurance performance. Whilst the theory appears sound, there is only one study showing an IMPROVEMENT in performance with a low carbohydrate diet18, with many showing no clear benefit of a low carbohydrate diet 19 ,20.    
“When the body is in ketosis, it lowers the blood pH level, causing the blood to become acidic. To counter this, the body takes calcium away from the bones,” she says. “The increased acidity in the body also increases uric acid, which can lead to the formation of kidney stones.” Therefore, it goes without saying that due to the stress an extremely low-carb diet can have on the body, those with kidney damage shouldn’t try to achieve ketosis or attempt the ketogenic diet. (10)
Ketosis also might cause weight loss in the beginning of a diet because of a loss of water weight. Ketosis causes your body to get rid of sodium and to release more urine. This can result in losing about 100 to 150 calories a day, just from this aspect of ketosis. This is weight that will likely be regained, however. Many diets that result in ketosis, namely low-carbohydrate diets, are low in calories as well, which can lead to weight loss. Nonetheless, it is often an unhealthily low number of calories.
This is the second shortest form of MCT, also rare and comprising about 8% of coconut oil. It is slower to turn into energy but less expensive than C8. XCT Oil is triple-distilled in a non-oxygen atmosphere with no solvents, and it contains C10 and C8, because these are the only two MCT oils that turn into ATP quickly without the liver. You would need 6 tablespoons of coconut oil to get one tablespoon of XCT oil.
Well I've been doing Keto for almost 3 months now and I feel great. I have more energy than I've add in a long time and I'm becoming more of a morning person now LOL. I feel so much better about how I look now and I've actually wanted to dress nice for work, actually tucking in my polo now instead of just leaving it out. Last couple of weeks I've been teetering between 200 and 205 lbs. SOOOOO close to Onederland. Just gotta keep at it and KCCO. I've been inspired by all the progress pics posted here so hopefully my 3 month pics can inspire some of you!!!!. Keep at it ya'll and remember the NSVs are sooooo much more important than what the scale says.

Given the choice of a fat and protein source like meat or a salt and carb rich food like potato chips, we are designed say yes to both. No matter how stuffed we are, the most primal parts of our brain will typically tell us that there is room for more if a novel food source is available. These behaviors were essential for our survival as a species. If we ate reasonably whenever food was available, then we wouldn’t have enough fat or muscle to fuel us when calories were scarce.
An increase in fat burning ability could decrease the efficiency of exercise: one adaptation to a high fat diet is an increase in a process called mitochondrial uncoupling. This means that some of the stored energy from metabolic substrates is not used to generate ATP but is ‘dissipated’ leading to a decrease in efficiency of energy production 26 ,19.  
The authors noted that “weight loss was similar between groups” [21]. However, they emphasized that “effects on atherogenic dyslipidemia (cholesterol) and glycemic control were still more favorable with a low-carbohydrate diet after adjustment for differences in weight loss.” [21] Another study noted that the low-carb diet promoted greater weight-loss than a standard low-fat diet for the first six months. However, these differences were small after one year. [22]
Christopher D. Gardner, PhD; Alexandre Kiazand, MD; Sofiya Alhassan, PhD; Soowon Kim, PhD; Randall S. Stafford, MD, PhD; Raymond R. Balise, PhD; Helena C. Kraemer, PhD; Abby C. King, PhD, “Comparison of the Atkins, Zone, Ornish, and LEARN Diets for Change in Weight and Related Risk Factors Among Overweight Premenopausal Women,” JAMA. 2007;297(9):969-977. http://jama.jamanetwork.com/art icle.aspx?articleid=205916.
I’ve been trying this keto diet that my dr.and daughter recommended, it’s been close to a week. I’ve changed my food intake, no bad carbs that I know of, was a huge chip addict stopped all that with no cravings. I’m not seeing any results I’m getting discouraged and everything sounds so complicated watching this, measuring that, I don’t have a clue what I’m doing. just that I stopped bread,pasta,poratoes,rice all those kind of carbs.I’m drinking more water eating green vegetables and trying to increase my fat intake. I don’t feel motivated to exercise which probably doesn’t help and have 100-130 to lose. I need help I don’t understand or have the time create a lot of meals and measure my fat,protein and carb intake.
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