How It Works On cyclical keto, also called keto cycling, you’ll cycle in and out of keto — usually on the diet for five days, followed by one or two days with more carbs. “The point of keto cycling is to make it easier for someone to follow,” Kizer says. “Every five to six days they can have the carbohydrates they’ve been entirely restricting.” There’s no set protocol of what your carb days should look like, but Kizer warns not to go overboard because that will make it more difficult for the body to return to ketosis.
Anticonvulsants suppress epileptic seizures, but they neither cure nor prevent the development of seizure susceptibility. The development of epilepsy (epileptogenesis) is a process that is poorly understood. A few anticonvulsants (valproate, levetiracetam and benzodiazepines) have shown antiepileptogenic properties in animal models of epileptogenesis. However, no anticonvulsant has ever achieved this in a clinical trial in humans. The ketogenic diet has been found to have antiepileptogenic properties in rats.[55]

Many neurological conditions share a common feature of impaired brain energy metabolism. It isn’t always clear if this impairment is the cause or the effect of the disease, but nonetheless, interventions that even partially restore or improve brain energy metabolism could help to prevent, slow or even reverse some conditions of the brain. Because ketones can: 1) get into the brain; 2) undergo metabolism by a distinct pathway that bypasses glucose metabolism, providing ketones by either following a ketogenic diet or by taking exogenous ketones could impact the natural course of some neurological conditions. 
I'm officially at the half way mark in my 2-week #ketogenicdiet, and I'm just now feeling like a complete human. The first 3-4 days I was seriously drained (#CardioIsHardio is putting it lightly), which is what I've heard to expect in the beginning. But this weekend, I hit up my go-to #barre studio, did some speed intervals on the bike, and got in some #kettlebell training, too. Ready to tackle this last week of #keto...then eat all the . Jk, kinda. #keto360 #healthyfats #ketosis

The low glycaemic index treatment (LGIT)[48] is an attempt to achieve the stable blood glucose levels seen in children on the classic ketogenic diet while using a much less restrictive regimen. The hypothesis is that stable blood glucose may be one of the mechanisms of action involved in the ketogenic diet,[9] which occurs because the absorption of the limited carbohydrates is slowed by the high fat content.[5] Although it is also a high-fat diet (with approximately 60% calories from fat),[5] the LGIT allows more carbohydrate than either the classic ketogenic diet or the modified Atkins diet, approximately 40–60 g per day.[3] However, the types of carbohydrates consumed are restricted to those that have a glycaemic index lower than 50. Like the modified Atkins diet, the LGIT is initiated and maintained at outpatient clinics and does not require precise weighing of food or intensive dietitian support. Both are offered at most centres that run ketogenic diet programmes, and in some centres they are often the primary dietary therapy for adolescents.[9]


I've tried that before(enzymedica digest gold for example) but it didn't seem to help much. It seems from testing that I have some heavy metal stuff going on and there might have been a chronic mold exposure in the past that is still reeking havoc and I imagine that might be affecting this pretty heavily. I will definitely be sticking to the avocadoes and coconut and 100% dark chocolate because I can't tolerate dairy. The hard part is figuring out what is the bare minimum of starch to make my gut feel good and be regular and at the same time become fat adapted and get those increased cognition and longevity benefits!!
In ketogenesis, two acetyl-CoA molecules instead condense to form acetoacetyl-CoA via thiolase. Acetoacetyl-CoA momentarily combines with another acetyl-CoA via HMG-CoA synthase to form hydroxy-β-methylglutaryl-CoA. Hydroxy-β-methylglutaryl-CoA form the ketone body acetoacetate via HMG-CoA lyase. Acetoacetate can then reversibly convert to another ketone body—D-β-hydroxybutyrate—via D-β-hydroxybutyrate dehydrogenase. Alternatively, acetoacetate can spontaneously degrade to a third ketone body (acetone) and carbon dioxide, although the process generates much greater concentrations of acetoacetate and D-β-hydroxybutyrate. When blood glucose levels are low, ketone bodies can be exported from the liver to supply crucial energy to the brain.[28]

Yes, the carb backloading approach can definitely help. Honestly I have SO MANY ARTICLES here on the site about sleep. Just go ahead and use the search bar for sleep and you'll find a plethora of info. For targeted sleep advice, I'd be happy to help you via a personal one-on-one consult. Just go to https://bengreenfieldfitness.com/coaching. and then choose a 20 or 60 minute consult, whichever you'd prefer. I can schedule ASAP after you get that.
A systematic review in 2016 found and analysed seven randomized controlled trials of ketogenic diet in children and young people with epilepsy.[2] The trials were done among children and young people for whom drugs failed to control their seizures, and only one of the trials compared a group assigned to ketogenic diet with a group not assigned to one.[16] The other trials compared types of diets or ways of introducing them to make them more tolerable.[2] Nearly 40% of the children and young people had half or fewer seizures with the diet compared with the group not assigned to the diet. Only about 10% were still on the diet after a few years.[2] Adverse effects such as hunger and loss of energy in that trial were common, with about 30% experiencing constipation.[16]
Wilder's colleague, paediatrician Mynie Peterman, later formulated the classic diet, with a ratio of one gram of protein per kilogram of body weight in children, 10–15 g of carbohydrate per day, and the remainder of calories from fat. Peterman's work in the 1920s established the techniques for induction and maintenance of the diet. Peterman documented positive effects (improved alertness, behaviour and sleep) and adverse effects (nausea and vomiting due to excess ketosis). The diet proved to be successful in children: Peterman reported in 1925 that 95% of 37 young patients had improved seizure control on the diet and 60% became seizure-free. By 1930, the diet had also been studied in 100 teenagers and adults. Clifford Barborka reported that 56% of those older patients improved on the diet and 12% became seizure-free. Although the adult results are similar to modern studies of children, they did not compare as well to contemporary studies. Barborka concluded that adults were least likely to benefit from the diet, and the use of the ketogenic diet in adults was not studied again until 1999.[10][14]
I just discovered your site and have been thoroughly enjoying many of the articles and appreciate that you get so in depth in your explanations. I’m in my late 40’s and, while not an extreme endurance athlete, I am moderately active with 18-20 mile rides 3x a week as well as some boxing and body weight resistance (push up, pull up, etc) mixed in. I’ve generally been paleo and stick to quality macros for the most part (grass fed meats/dairy, organic veg and oils) and zero supplements. I recently started following keto (after reading this article) about 10 days ago and things seem good thus far. I do, however, want to avoid any of the negative side effects you mention and also not lose any lean muscle. I’m currently about 174 lbs, 5’8″ and about 19% bodyfat – I’m taking in about 95g protein, 130g fat and <20g net carbs. I'm eating all quality – wild salmon, grass fed beef, pastured eggs, coconut oil, Brain Octane and Grass fed butter in coffee, sardines, etc. With a smattering of organic veg, but it seems real easy to bust through the carb barrier. *I'M ALSO TAKING KETOCANA PRE-WORKOUT* and I notice this is keeping me going throughout a ride or the gym.
I was diagnosed in April with type 2 diabetes. I have learned A LOT about carbs and how they affect a diabetic’s blood sugar. They are the enemy! I looked at the Keto diet and adapted parts of it to my dietary needs. I try to limit my carb intake to 20 grams a day, far less than what the American Diabetes Association recommends. I experimented eating a variety of carbs like oatmeal, pasta, fresh fruits, yogurt and all spike my blood glucose readings well above 30 points. Learning what I have I think it’s prudent for anyone to manage their carb intake closely, especially if they are NOT physically active. Exercise has a huge in pact in reducing blood glucose. My goal is to manage my diabetes without drugs instead with diet and exercise.
Plus, it's not like I couldn't feed my body anything until noon. Low-carb keto drinks such as tea, water, and coffee were all options, and Dr. Axe suggested adding protein (such as his bone broth or collagen protein powders) to my liquids to help fend off hunger. So, throughout my two weeks, I experimented with Dr. Axe's bone broth protein and collagen protein, as well as unsweetened nondairy milks such as almond and oat milk. I'll cut to the chase on this one: While expert opinion is mixed on the bioavailability of collagen powder and its potential health benefits, through trial and error, I landed on coffee with oat milk and collagen peptides as my go-to morning brew. I also took some of Dr. Axe's Keto Fire supplements in the morning. They contain exogenous ketones, which is a fancy way of saying bonus ketones my body doesn't produce on its own.
Came across this old pic yesterday and wanted to compare it to my recently uploaded pic. This was from when I was doing an all fruit / starch vegan diet. I also consumed gluten here and there.. thank God I got tested for food sensitivities or I would be in poor health still. Nothing against the vegan diet, but everyone’s body is different. People have had success with veganism and people who are insulin resistant haven’t. So glad I found Keto thanks to @jason.wittrock 💪🏻 - - - - - - - #waronsugar #keto #ketoquest #fitness #transformationtuesday #journey #fatloss #hardwork #progress #shred #workout #fitnesswomen #fitnessmotivation #bodybuilding #weightloss #weightlossjourney
It's worth noting that the review focused on low-carbohydrate diets, which are not always ketogenic. To be sure, there are balanced ways to adopt the ketogenic diet, and it can beneficial to some. In addition to its proven weight-loss effects that can be especially helpful for obese people, the diet is also a proven treatment for children with epilepsy. That's because the state of ketosis produces a natural chemical called decanoic acid, which can reduce seizures.
Obesity means that someone has an excess amount of fat to the extent that it harms your health. Oftentimes, doctors, nurses, and other professionals will put your weight in terms of your height and gender in a figure called body mass index (BMI). According to the World Health Organization, a BMI from 25-30 usually indicates someone is overweight, BMI in the 30-35 range puts someone in the range of being obese and 35 and over morbidly obese. [1]

Obesity means that someone has an excess amount of fat to the extent that it harms your health. Oftentimes, doctors, nurses, and other professionals will put your weight in terms of your height and gender in a figure called body mass index (BMI). According to the World Health Organization, a BMI from 25-30 usually indicates someone is overweight, BMI in the 30-35 range puts someone in the range of being obese and 35 and over morbidly obese. [1]
When glucose levels are low, especially over time, most cells will switch to using ketone bodies for fuel. Ketones allow cells to be metabolically flexible, so to speak. Even the brain and nerve cells, which are heavily dependent on glucose can utilize ketone bodies for fuel. This ability of most normal cells to use ketones when glucose is unavailable indicates that their cellular mitochondria are healthy and functioning properly. 
Some investigators feel that mitochondrial dysfunction and compromised brain glucose metabolism may play a role in the development of autism. As autism is sometimes accompanied by seizures such as those seen in epilepsy (which could be improved by the ketogenic diet), the diet has been trialled in a small number of case studies. These cases have shown that the ketogenic diet can lead to improvements in the childhood autism rating scale score 78 ,79, however dietary adherence may prove even more of a challenge with these children, decreasing the viability of the ketogenic diet as an intervention.   
Carbohydrate: Most of what determines how ketogenic a diet is will depend on how much carbohydrate is eaten, as well the individual's metabolism and activity level. A diet of less than 50 or 60 grams of net (effective) carbohydrate per day is generally ketogenic. Some sources say to consume no more than 20 grams of carbohydrates per day, while others cite up to 50 grams, and many recommend no more than 5 percent of calories from carbs. However, athletes and people with healthy metabolisms may be able to eat 100 or more grams of net carbohydrate in a day and maintain a desired level of ketosis. At the same time, an older sedentary person with Type 2 diabetes may have to eat less than 30 net grams to achieve the same level.
Ketones are produced if you eat minimal carbs and very moderate amounts of protein. On the keto diet, your body is fuelled almost entirely on fat. Your insulin levels drop and fat burning escalates. Optimal ketone levels are beneficial for weight loss, health, and also offer mental and physical performance benefits. You’ll be less hungry and also have a steady supply of energy.
If you’re following the keto diet, you will need protein, but you should limit your intake to about 20 percent of your total daily calories. (1) This is important because when you consume more protein than you need, your body converts the excess protein into carbs through a process called gluconeogenesis. This process pushes your body out of ketosis.

A high-fat diet also trains your body to burn even more fat during exercise, even at high intensities. Fat is released faster and in greater amounts from your storage adipose tissue and transported more quickly into your muscles and mitochondria. Your muscles also store more energy as fat and use this fat-based fuel more efficiently and quickly. Even more interestingly, a high-fat diet can cause a shift in the gene expression that codes for specific proteins that increase fat metabolism – and create very similar adaptations to exercise itself. So the mere act of shifting primary fuel intake from carbohydrates to fat begins to make you more “fit”, even if you’re not exercising.
Normally, the body breaks down carbohydrates, fat, and (sometimes) proteins to provide energy. When carbohydrate is consumed in the diet, some is used immediately to maintain blood glucose levels, and the rest is stored. The hormone that signals to cells to store carbohydrate is insulin. The liver stores carbohydrate as glycogen, this is broken down and released between meals to keep blood glucose levels constant. Muscles also store glycogen, when broken down this provides fuel for exercise. Most cells in the body can switch readily between using carbohydrates and fat as fuel. Fuel used depends on substrate availability, on the energy demands of the cell and other neural and hormonal signals. 
Still, I enjoy cooking and I plan my meals on the regular anyway. With a keto food list in hand and advice from Dr. Axe in my mind, I filled my grocery cart with family-size versions of what I regularly buy (apples, berries, nut butter, kale), and a lot more meat than I ever have in my cart at one time (ground lamb, chicken, REAL bacon). What was missing? Some of my usual high-carb items, like whole-grain English muffins, orange juice, butternut squash, and tortilla chips.

-Cardiovascular Disease: High blood sugar has been shown to increase the risk for cardiovascular events, cardiovascular disease, and cardiovascular mortality—while lower glucose levels result in lower cardiovascular risk. Coronary artery disease risk has been shown to be twice as high in patients with impaired glucose tolerance, compared with patients with more normal glucose tolerance. The risk for stroke increases as fasting glucose levels rise above 83 mg/dL. In fact, every 18 mg/dL increase beyond 83 results in a 27 percent greater risk of dying from stroke. Incidentally, glucose can “stick” to cholesterol particles and render these particles extremely dangerous from a heart health standpoint, which is why it’s all the more important to control blood sugar levels if you’re eating a “high-fat diet.”
Pretty soon, I became scared to eat too much protein for fear that it would turn into sugar via gluconeogenesis. I became scared of fruit and many vegetables. I became scared to eat out for fear of things being cooked in unhealthy oils. I didn’t celebrate my kid’s birthdays with pizza and cake because God forbid I eat that many carbs and get kicked out of ketosis. I became obsessed with tracking my fat intake and trying to get it lower and lower, spending so much time planning my day so I would never go over that 5% carb intake. I started losing energy. I got really, really bloated and couldn’t figure out why.
Physical or mental fatigue during workouts (or while you’re sitting at your office) is caused by the low blood glucose that occurs as your carbohydrate fuel tank approaches empty (also known as the infamous “bonk”, which is awesomely demonstrated in this funniest running cartoon I’ve ever seen). Because it is generally (and sadly) accepted as orthodox knowledge that the human body can’t burn fat as a reliable fuel source – especially when you’re exercising for long periods of time or at high intensities – nearly every shred of nutrition science is simply looking for ways to somehow increase the size of your carbohydrate fuel tank and hack the body to allow it to store more carbs or absorb carbs more quickly.
A reduced availability of dietary carbohydrates leads to an increased liver production of KBs. The liver cannot utilize KBs because it lacks the mitochondrial enzyme succinyl-CoA: 3-ketoacid (oxoacid) CoA transferase (SCOT) necessary for activation of acetoacetate to acetoacetyl CoA. KBs are utilized by tissues, in particularly by brain. KBs enter the citric acid cycle after being converted to acetyl CoA by hydroxybutyrate dehydrogenase (HBD), succinyl-CoA: 3–CoA transferase (SCOT), and methylacetoacetyl CoA thiolase (MAT). Modified from Owen (2005), Paoli et al. (2014).

My doctor recommended a keto diet for me despite me having an eating disorder and being vegan. It has been so difficult to try to follow that it has made everything worse. My eating disorder is worse, my depression is worse, my anxiety around food is through the roof. I am so glad I found your article because it’s been so hard finding anything anti-keto! I needed to read that it was driving other people crazy too and was dangerous, so thank you. I am slowly reintegrating carbs but i do believe a lot of damage has been done in regards to my psychological health that it will take a long time to recover from this “diet”.
There are numerous benefits that come with being on keto: from weight loss and increased energy levels to therapeutic medical applications. Most anyone can safely benefit from eating a low-carb, high-fat diet. Below, you’ll find a short list of the benefits you can receive from a ketogenic diet. For a more comprehensive list, you can also read our in-depth article here >
In fact, he says my already somewhat balanced diet is part of why I didn't experience the keto flu. (Some people report feeling sick to their stomach, irritable, and dizzy, among other flu-like symptoms, for the first few days or even weeks of keto.) People who transition from a very high-carb and high-protein diet to a high-fat diet are more susceptible to these rare but extreme symptoms, he says. This is why he says he built a Feast Phase—when you're adding fats into your diet without really restricting your carbs—into his Keto360 plan as a way to ease your body into ketosis. "If someone is a fairly good eater, and they already do have a moderate amount of fat in their diet—not high fat but moderate—typically they'll transition pretty well," he says.
Ketogenic diets are, however, a well-established way to help control Type 2 diabetes, and the plan has for nearly 100 years been used to reduce instances of childhood epileptic seizures. Some scientists also think the high-fat diet may hold promise for staving off Alzheimer's, and there are some early indications it might help improve certain cancer treatment outcomes when used in conjunction with drugs. (Harper is part of a research team investigating how the diet might help boost treatment among people with breast cancer.)
I learned a long time ago not to be obsessed with diets for wt. loss. 3 weeks ago I reached a crisis with type II diabetes however and just knew I had to make drastic changes to get it under control. I found the keto diet to be the closest to an extreme decrease in carbs and decided to try it. I these 3 weeks my blood sugar has dropped from 175 to 300 down to 98 to 140. I’ve dropped my insulin from 4 short acting shots and one long acting each day to just the one long acting – and decreased that dose from 55 units to 30. Now I feel stuck on keto, but have the same issues with it that you speak of. Will be trying to tweak it as much as I can to satisfy tastes and convenience yet stay with better blood sugar control. Wt. loss would be nice, but not a main concern, lost 5 lbs so far, but may be just fluid as you say.
Early studies reported high success rates: in one study in 1925, 60% of patients became seizure-free, and another 35% of patients had a 50% reduction in seizure frequency. These studies generally examined a cohort of patients recently treated by the physician (what is known as a retrospective study) and selected patients who had successfully maintained the dietary restrictions. However, these studies are difficult to compare to modern trials. One reason is that these older trials suffered from selection bias, as they excluded patients who were unable to start or maintain the diet and thereby selected from patients who would generate better results. In an attempt to control for this bias, modern study design prefers a prospective cohort (the patients in the study are chosen before therapy begins) in which the results are presented for all patients regardless of whether they started or completed the treatment (known as intent-to-treat analysis).[18]

Got a salad today from Subway, and was really happy with it! I basically ordered the same sandwich I would always get but ordered it as a salad instead of a sub. Cold cut combo with all the veggies (minus jalapeño and olives) and mayo. It was great, and huge! I stuffed myself and only ate half, and hey chopped up all the meat and veggies which I wasn’t expecting. Definitely recommend!
Note: Are you a vegetarian or vegan and want to go on a ketogenic diet? It’s still possible! Just keep in mind that the dietary restrictions can sometimes be a little bit intense. Make sure to plan ahead and prepare to aid your success. To help out, we’ve published articles (with 7 day meal plans included) for both the vegetarian ketogenic diet and the vegan ketogenic diet.

Achieving ketosis is a pretty straightforward, but it can seem complicated and confusing with all of the information out there.4If you want to learn more about ketosis and the scientific process around it, you can visit a very in-depth discussion about on Dr. Peter Attia’s website. Here’s the bottom line on what you need to do, ordered in levels of importance:


Fasting is another way to achieve ketosis. This doesn’t suggest going days without food, but rather intermittent fasting. You can eat for eight hours and then fast for 16 hours, or eat a low-calorie diet for a few days (about 1,200 daily calories if you’re a woman and 1,500 daily calories if you’re a man). As you take in less food, your body uses more of its fat stores for fuel.

Urine strips or sticks: Ketone urine strips indicate ketone quantity on a color-grading scale. Urine tests are affordable and easy to use. However, be wary of inaccurate results. Urine tests only monitor leftover, unused ketones in your body. That’s why the strips will be darker, indicating more ketones, when you’re new to the diet. As you adapt to ketosis, your body uses more ketones, so there will be fewer ketones expelled through your urine. Being well-hydrated can also throw off tests.
I will admit to appeal to authority here. This was said by the professor of the course I mentioned in my previous post, but it was also confirmed by many of my classmates, whom, at this point(for reasons, which are too tedious and long winded to extrapolate on atm), I consider smart enough to know their business, that I choose to believe them. All of them. If nothing else, the professor himself is,well… authority on his field.
Next, you need to ease yourself into this stuff. As I mentioned earlier, KETO//OS is blended with MCT’s, which can cause digestive distress if you’re not used to consuming them. This is due to the fact that your body has not yet adapted to the increased fats in your diet, and is less efficient at utilizing ketones as its fuel source. Once your body has adapted to MCT in the diet, the digestive distress will resolve.  But I recommend you start slowly with just about a half a serving a day, and over two weeks, build up to a full serving twice a day.
For those who love their potatoes, pasta, and even fruit, this is a diet that will change your lifestyle completely. You’ve probably already guessed that the pasta and other wheat foods are not allowed. Potatoes and other starchy foods, like legumes and beans, are also on the banned list and that makes sense to many. But fruit? Is fruit not allowed?
I am hoping that keto had nothing to do with it. He expressed to be on several occasions that he felt the best he'd ever felt in his life while doing keto. After he died I went to a cardiologist to be checked out and my heart is fine. Dr said he actually supports keto in the lean meat and veggies vs of it plus healthy fats. Not a ton of red meat etc. Also highly supports intermittent fasting.

I’m honestly a little skeptical about it the idea of keto permanently. My brief glance at the literature seems to imply that it can have side effects of kidney stones, skeletal fractures, and slow the growth rate of children, but that was a study on kids with epilepsy (which it treated very effectively), so who knows how that applies to adults. And the other studies I found dealt with overweight and obese subjects, so it may be hard to find something on the long term effects on otherwise healthy adults.


Day 3: I'm tired AF. Like the kind of tired when you're so exhausted you have to use your left arm to lift your right arm. Somehow, I pried myself out of bed to work out only to realize cardio has never been more hardio, so some chill strength training was going to have to do. (I Now Know These 8 Things About Exercising While On the Keto Diet.) Nonetheless, feelings of lethargy were to be expected, says Dr. Axe, who says days 2 and 3 were also the hardest for him the first time he tried keto. "Every body is different," he assures me. "Some people feel better by day 5, others take two weeks."
An interview with University of Florida researcher and scientist Dominic D’ Agostino. In that episode, “A Deep Dive Into Ketosis: How Navy Seals, Extreme Athletes & Busy Executives Can Enhance Physical and Mental Performance With The Secret Weapon of Ketone Fuel“, Dominic highlights his research into the use of ketones to enhance breathhold time and reduce the brain’s requirements for oxygen.

These findings fall in line with another meta-analysis on 13 randomized controlled trials that compared low-fat and low-carbohydrate diets. The researchers found that, after six months, subjects who consumed less than 60 grams of carbohydrates per day had an average weight loss that was 8.8 pounds greater than the subjects on low-fat diets. At one year, the difference had fallen to 2.3 lb (which is consistent with what was found in the meta-analysis conducted by the Brazilian researchers).


It’s Best for People Who ... have a tough time sticking to keto. “It can be helpful if someone wants to take a break and have carbs,” says Koche. That may not be easy for everyone. Kizer worries this approach may promote carb binging. You may have heard keto cycling recommended for athletes, who use the extra carbohydrates to fuel their workouts or competitions. But no existing published science backs this up, though studies, including an April 2018 study published in The Journal of Sports Medicine and Physical Fitness, have shown that the keto diet does hinder exercise performance.
This is because you get rid of the foods that cause high blood sugar, also known as glucose. Glucose is the easiest way for your body to get energy, but it can lead to energy crashes if you get too much in a short time. To get rid of the glucose and use it up, the body needs to produce insulin. As we produce more and more, our bodies become resistant to it, and this can lead to diabetes.
I’ve been on the Wheat Belly Diet over 2 years. You have to read the book on it by Dr. Allen Wolfelt. It works. Basically you’re cutting out grains do to the GMO. No wheat or corn, cousins of, or biproctucts of. It took some getting use to, and adjustments. I started out with certain things and worked my way. You’d have to read his book. I’m making it my life style, rest of my life.
So people saying that – despite the lack of scientific support – likely have a financial reason to say it. Some of these products are sold under something like a multi-level marketing arrangement, so sales people are entirely paid based on commission. For example, the company Prüvit sells drinkable ketones, called KETO//OS with a multi-level marketing structure.
C8 is the rarest MCT found in coconut oil, comprising about 6% of coconut oil. It has potent anti-microbial properties (way more potent than lauric acid) to help you maintain a healthy gut, and it is the fastest MCT to metabolize in the brain. (hence the name Brain Octane). Your liver does not need to process C8, and it only takes the steps for your body to turn it into ATP cellular energy (sugar takes 26 steps). You would need 18 tablespoons of coconut oil to get just one tablespoon of Brain Octane.
Fascinating stuff and I am quite curious how we know for certain one is actually in ketosis i.e. using ketones as primary fuel source BECAUSE we do know that glucose has a shorter metabolic pathway to burn and under most conditions, given the presence of glucose, that is what the body will default to which is why high fat and high sugar together in diet is so detrimental. So if we use one or more of the above “boosters” and show high levels of blood ketones but also highish levels of glucose (during initial transition) will be mostly burning ketones or still defaulting to glucose?

Let’s hold up a sec. Allow me to introduce you to the DIETFITS Randomized Clinical Trial, published in February 2018 in the Journal of the American Medical Association. DIETFITS, which stands for Dietary Intervention Examining the Factors Interacting with Treatment Success, succeeded in busting a slew of dietary theories. Microbiome is responsible for everything? Nope. Predisposition to success on one diet based on genetics? Nah. Low carb over low fat? Uh-uh.
It is possible to combine the results of several small studies to produce evidence that is stronger than that available from each study alone—a statistical method known as meta-analysis. One of four such analyses, conducted in 2006, looked at 19 studies on a total of 1,084 patients.[22] It concluded that a third achieved an excellent reduction in seizure frequency and half the patients achieved a good reduction.[3]

Wow! Such an informative article! A lot to take in! Loving that you mentioned the KETO//OS! I’ve actually lost 10 lbs in 3 weeks! Kinda cool. I haven’t heard of the other products but I’m excited the check them out! Also, the breath tool is new to me. Thank you! If anyone wants to checkout my testimonial with epilepsy, weight loss on the KETO//OS you can read it here: http://bit.ly/keto-os
As a matter of fact, from a pure biology perspective, lauric acid should actually be considered a LCT, because unlike C8 and C10 forms of MCT, lauric acid gets processed by your liver. This matters because your body metabolizes MCT’s differently than LCT’s: unlike LCT’s, MCT’s get very quickly converted into ketone energy to fuel your brain and body instead of requiring a pit stop in the liver for processing.
In sheep, ketosis, evidenced by hyperketonemia with beta-hydroxybutyrate in blood over 0.7 mmol/L, occurs in pregnancy toxemia.[78][79] This may develop in late pregnancy in ewes bearing multiple fetuses,[78][79] and is associated with the considerable glucose demands of the conceptuses.[80][81] In ruminants, because most glucose in the digestive tract is metabolized by rumen organisms, glucose must be supplied by gluconeogenesis,[82] for which propionate (produced by rumen bacteria and absorbed across the rumen wall) is normally the principal substrate in sheep, with other gluconeogenic substrates increasing in importance when glucose demand is high or propionate is limited.[83][84] Pregnancy toxemia is most likely to occur in late pregnancy because most fetal growth (and hence most glucose demand) occurs in the final weeks of gestation; it may be triggered by insufficient feed energy intake (anorexia due to weather conditions, stress or other causes),[79] necessitating reliance on hydrolysis of stored triglyceride, with the glycerol moiety being used in gluconeogenesis and the fatty acid moieties being subject to oxidation, producing ketone bodies.[78] Among ewes with pregnancy toxemia, beta-hydroxybutyrate in blood tends to be higher in those that die than in survivors.[85] Prompt recovery may occur with natural parturition, Caesarean section or induced abortion. Prevention (through appropriate feeding and other management) is more effective than treatment of advanced stages of ovine ketosis.[86]

Your individual fat adaptation period. Remember your body needs time to become fat-adapted and that time depends on your metabolism. For instance, if you’re coming off a Standard American Diet (SAD) and your adult body has never ran on ketones before, your adaptation period might take a little longer. You’ll only experience the true weight loss effects of keto when your body is actually running on ketones.

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